Jasplakinolide

• Supplier: Tocris Bioscience
• Catalog: 6148
• Prices: $309.00
• Sizes: 100 µg
• Cas Number: 102396-24-7
• Chemical Name: Cyclo[(3R)-3-(4-hydroxyphenyl)-β-alanyl-(2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-L-alanyl-2-bromo-N-methyl-D-tryptophyl]
• Formula: C36H45BrN4O6
• Molecular Weight: 709.67
• Purity: >97 %
• Description: Rapidly stabilizes pre-formed actin filaments and inhibits their disassembly in vitro . Also induces polymerization of actin monomers into F-actin in vivo . Shown to bind to F-actin competitively with phalloidin (Cat. No. 4535) (K d ~ 15 nM). Exhibits antifungal and antiproliferative effects (IC 50 = 35 nM for antiproliferative activity in PC3 cells). Cell permeable.