β -Lapachone

• Supplier: Tocris Bioscience
• Catalog: 6146
• Prices: $109.00, $459.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 4707-32-8
• Chemical Name: 3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione
• Formula: C15H14O3
• Molecular Weight: 242.27
• Purity: >98 %
• Description: DNA topoisomerase I inhibitor. Exhibits a different inhibitory mechanism to camptothecin (Cat. No. 1100). Induces apoptosis in a variety of cell lines, including prostate cancer and promyelocytic leukemia cells; blocks the cell cycle in G 0 /G 1 . Also has effects on DNA topoisomerase II, NF- κ B, AP-1, and JNK.