Name | MS 023 dihydrochloride |
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Supplier | Tocris Bioscience |
Catalog | 5780 |
Prices | $229.00, $945.00 |
Sizes | 10 mg, 50 mg |
Function Type | Inhibitor |
Chemical Name | N1-Methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediaminedihydrochloride |
Formula | C17H25N3O.2HCl |
Molecular Weight | 360.32 |
Purity | >98 % |
Description | Potent and selective type I PRMT inhibitor (IC 50 values are 8, 8, 30, 83 and 119 nM for PRMT6, PRMT8, PRMT1, PRMT4 and PRMT3, respectively). Exhibits no significant activity against type II and III PRMTs, PKMTs, DNMTs, KDMs and reader proteins. Reduces global arginine asymmetric dimethylation levels in vitro . |
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