| Name | NSC 23766 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5779 |
| Prices | $139.00, $585.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 1177865-17-6 |
| Chemical Name | N6-[2-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediaminetrihydrochloride |
| Formula | C24H35N7.3HCl |
| Molecular Weight | 530.97 |
| Purity | >99 % |
| Description | Selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC 50 ~ 50 μ M) without affecting Cdc42 or RhoA activation. Inhibits Rac1-mediated cell functions and is reported to reverse tumor cell phenotyes in prostate cancer cells. |
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