PF 06447475

Name PF 06447475
Supplier Tocris Bioscience
Catalog 6114
Prices $169.00, $705.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 1527473-33-1
Chemical Name 3-[4-(4-Morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile
Formula C17H15N5O
Molecular Weight 305.33
Purity >98 %
Description Potent LRRK2 inhibitor (IC 50 = 3 nM). Attenuates α -synuclein-induced dopaminergic neurodegeneration and neuroinflammation in G2019S-LRRK2 expressing rats. Also neuroprotective in wild type rats. Brain penetrant.
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