PF 184

Name PF 184
Supplier Tocris Bioscience
Catalog 6169
Prices $279.00
Sizes 10 mg
Function Type Inhibitor
Cas Number 1187460-81-6
Chemical Name 8-[[[5-Chloro-2-[3,4-dimethyl-3,4-bis(hydroxymethyl)-1-pyrrolidinyl]-4-pyridinyl]carbonyl]amino]-1-(4-fluorophenyl)-4,5-dihydro-1H-benz[g]indazole-3-carboxamide
Formula C32H32ClFN6O4
Molecular Weight 619.09
Purity >98 %
Description Potent and selective IKK β inhibitor (IC 50 = 37 nM). Displays selectivity over 85 other kinases. Inhibits IL-1 β -induced TNF- α production in a steroid-insensitive in vitro model of oxidative stress.
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