Name | RN 1 dihydrochloride |
---|---|
Supplier | Tocris Bioscience |
Catalog | 5909 |
Prices | $195.00, $805.00 |
Sizes | 10 mg, 50 mg |
Function Type | Inhibitor |
Cas Number | 1781835-13-9 |
Chemical Name | 1-(4-methyl-1-piperazinyl)-2-[[(1R*,2S*)-2-[4-phenylmethoxy)phenyl]cyclopropyl]amino]ethanonedihydrochloride |
Formula | C23H29N3O2.2HCl |
Molecular Weight | 452.42 |
Purity | >97 % |
Description | Potent lysine specific demethylase 1 (LSD1) inhibitor (IC 50 = 70 nM). Exhibits selectivity for LSD1 over MAO-A and MAO-B (IC 50 values are 0.51 and 2.79 μ M for MAO-A and MAO-B, respectively). Impairs long-term, but not short-term memory in mice. Brain penetrant following systemic administration. |
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