Ro 8-4304 hydrochloride

Name Ro 8-4304 hydrochloride
Supplier Tocris Bioscience
Catalog 5913
Prices $159.00, $665.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 1312991-77-7
Chemical Name 4-[3-[4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1(2H)-pyridinyl]-2-hydroxypropoxy]benzamidehydrochloride
Formula C21H23FN2O3.HCl
Molecular Weight 406.88
Purity >99 %
Description NMDA receptor antagonist (IC 50 = 0.4 μ M) that displays > 100 fold selectivity for NR2B-containing receptors over NR2A-containing receptors. Exhibits an activity-dependent mechanism of NMDA antagonism and is competitive with respect to spermine (Cat. No. 0958).
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