Name | GPR120 Agonist IV, cpdA - CAS 1599477-75-4 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 533469 |
Cas Number | 1599477-75-4 |
Formula | C₁₉H₂₃ClF₃NO₃ |
Purity | ≥97% by HPLC |
Description | A cell-permeable azaspiroundecanyl acetic acid compound that acts as a selective Gpr120 (FFAR4) agonist toward both human and murine species (EC 50 = 60 nM/IP 3 production and 350 nM/β-Arrestin-2 recruitment using cells expressing human or murine Gpr120), while being ineffective toward Gpr40 and is about 100-fold more effective than docosahexaenoic acid/DHA in stimulating serum response element/SRE promoter-mediated reporter transcription in mGPR120-expressing HEK 293 |
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