GPR120 Agonist IV, cpdA - CAS 1599477-75-4 - Calbiochem

Name GPR120 Agonist IV, cpdA - CAS 1599477-75-4 - Calbiochem
Supplier EMD Millipore
Catalog 533469
Cas Number 1599477-75-4
Formula C₁₉H₂₃ClF₃NO₃
Purity ≥97% by HPLC
Description A cell-permeable azaspiroundecanyl acetic acid compound that acts as a selective Gpr120 (FFAR4) agonist toward both human and murine species (EC 50 = 60 nM/IP 3 production and 350 nM/β-Arrestin-2 recruitment using cells expressing human or murine Gpr120), while being ineffective toward Gpr40 and is about 100-fold more effective than docosahexaenoic acid/DHA in stimulating serum response element/SRE promoter-mediated reporter transcription in mGPR120-expressing HEK 293
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