| Name | (Z)-4-Hydroxytamoxifen |
|---|---|
| Supplier | BioGems |
| Catalog | 6800637 |
| Prices | $120.00, $360.00 |
| Sizes | 5 mg, 25 mg |
| Function Type | Inhibitor |
| Cas Number | 68047-06-3 |
| Chemical Name | 4-[(Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol |
| Formula | C26H29NO2 |
| Molecular Weight | 387.5 |
| Purity | ≥98% |
| Description | Tamoxifen is a modulator of the of the estrogen receptor, with tissue specific agonistic and antagonistic effects. (Z)-4-Hydroxytamoxifen is a Tamoxifen metabolite with increased potency and a 100x higher affinity for the estrogen receptors. It is also reported to inhibit lipid peroxidation and can be used to activate intein-linked or estrogen receptor ERT2 domain fused Cas9 to reduce off target effects in CRISPR-mediated gene editing. |
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