LGK974

Name LGK974
Supplier BioGems
Catalog 1241454
Prices $65.00, $180.00
Sizes 1 mg, 5 mg
Function Type Inhibitor
Cas Number 1243244-14-5
Chemical Name 2-[5-methyl-6-(2-methylpyridin-4-yl)pyridin-3-yl]-N-(5-pyrazin-2-ylpyridin-2-yl)acetamide
Formula C23H20N6O
Molecular Weight 396.4
Purity ≥98%
Description LGK974 is a highly potent inhibitor of Porcupine (PORCN), a Wnt-specific acyltransferase. LGK974 is orally bioavailable and inhibits WNT signaling in vitro and in vivo. It is reported to exhibit anti-tumor properties without increasing cytotoxicity.
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