MK-2206 dihydrochloride

Name MK-2206 dihydrochloride
Supplier BioGems
Catalog 1031320
Prices $110.00, $385.00
Sizes 5 mg, 25 mg
Function Type Inhibitor
Cas Number 1032350-13-2
Chemical Name 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-2H-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-one;dihydrochloride
Formula C25H21N5O2HCl
Molecular Weight 480.4
Purity ≥98%
Description MK-2206 is a highly allosteric selective Akt1,2,3 (IC50 5nM, 12nM, 65nM) inhibitor. It is reported to inhibit the proliferation of cancer cell lines when used synergistically with cytotoxic agents such as erlotinib or lapatinib and significantly enhances cell apoptosis.
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