| Name | Ruxolitinib |
|---|---|
| Supplier | BioGems |
| Catalog | 9414958 |
| Prices | $135.00, $350.00 |
| Sizes | 5 mg, 25 mg |
| Function Type | Inhibitor |
| Cas Number | 941678-49-5 |
| Chemical Name | (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile |
| Formula | C17H18N6 |
| Molecular Weight | 306.4 |
| Purity | ≥98% |
| Description | Ruxolitinib is a potent Janus-associated Kinase (JAK1 IC50 2.7nM, JAK2 IC50 4.5nM) inhibitor. JAK1 and JAK2 transduce cytokine-mediated signals and are involved in interferon-gamma signaling. Ruxolitinib is reported to block IL-6 signaling and inhibits the proliferation of erythroid progenitors. |
| Supplier Page | Shop |