Name | 2’3’-cGAMP |
---|---|
Supplier | BioGems |
Catalog | 1446640 |
Prices | $275.00, $525.00 |
Sizes | 500 µg, 1 mg |
Function Type | Agonist |
Cas Number | 1441190-66-4 |
Chemical Name | 2'-O,5'-O-((adenosine-3'-O,5'-O-diyl)bisphosphinico)guanosine |
Formula | C20H24N10O13P2 |
Molecular Weight | 674.4 |
Purity | ≥98% |
Description | 2’3’-cGAMP binds to STING (stimulator of IFN genes) and functions as an endognous second messenger to activate the innate immune system. It is produced by the cyclic GMP-AMP synthase (cGAS) from ATP and GTP upon cytosolic DNA stimulation. |
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