8-Bromo-cAMP

Name 8-Bromo-cAMP
Supplier BioGems
Catalog 2354843
Prices $100.00, $300.00
Sizes 25 mg, 100 mg
Function Type Agonist
Cas Number 23583-48-4
Chemical Name (4aR,6R,7R,7aS)-6-(6-amino-8-bromopurin-9-yl)-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
Formula C10H11BrN5O6P
Molecular Weight 408.1
Purity ≥95%
Description 8-Bromo-cAMP is a cell-permeable brominated derivative of cAMP that is longer lasting due to a higher resistance to cyclic AMP phosphodiesterase. cAMP activates protein kinases, used for intracellular signal transduction, and regulates the function of ion channels. 8-Bromo-cAMP is reported to enhance the induction of pluripotency in human fibroblast cells and protects neutrophils against TNF-α-induced apoptosis.
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