AZD 3147

Name AZD 3147
Supplier Tocris Bioscience
Catalog 6060
Function Type Inhibitor
Cas Number 1101810-02-9
Chemical Name N-[4-[4-[1-(Cyclopropylsulfonyl)cyclopropyl]-6-[(3S)-3-methyl-4-morpholinyl]-2-pyrimidinyl]phenyl]-N'-(2-hydroxyethyl)thiourea
Formula C24H31N5O4S2
Molecular Weight 517.66
Purity >98 %
Description Potent and selective dual mTORC1 and 2 inhibitor (IC 50 = 1.5 nM). Exhibits >300-fold selectivity for mTOR over PI 3-kinase isoforms. Orally bioavailable.
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