CC4

• Supplier: Tocris Bioscience
• Catalog: 6258
• Function Type: Agonist
• Cas Number: 492-02-4
• Chemical Name: (1R,5S)-1,2,3,4,5,6-Hexahydro-3-[2-[(1R,5S)-1,5,6,8-tetrahydro-8-oxo-1,5-methano-2H-pyrido[1,2-a][1,5]diazocin-3(4H)-yl]ethyl]-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one
• Formula: C24H30N4O2
• Molecular Weight: 406.52
• Purity: >98 %
• Description: High affinity and subtype selective α 6 β 2 and α 4 β 2 partial agonist (K i values are 12 and 26nM for rat α 6 β 2 and α 4 β 2 receptors respectively). Has low affinity for α 3 β 4 and α 7 receptors (K i values are 4.8 and 13 μ M for human α 3 β 4 and rat α 7 receptors respectively). Stimulates dopamine release from striatal slices in vitro . Attenuates nicotine-induced self-administration and conditional place preference in rats.