CDN 1163

• Supplier: Tocris Bioscience
• Catalog: 5821
• Function Type: Activator
• Cas Number: 892711-75-0
• Chemical Name: 4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide
• Formula: C20H20N2O2
• Molecular Weight: 320.38
• Purity: >98 %
• Description: SERCA2 allosteric activator. Increases Ca 2+ -ATPase activity and Ca 2+ uptake by ER microsomes from obese mice. Rescues HEK cells from ER stress-induced cell death. Reduces fasting glucose levels and adipose tissue weight, and increases energy expenditure in ob/ob mice. Also improves glucose tolerance and reverses hepatic steatosis in ob/ob mice.