DBM 1285 dihydrochloride

• Supplier: Tocris Bioscience
• Catalog: 6175
• Function Type: Inhibitor
• Chemical Name: N-Cyclopropyl-4-[4-(4-fluorophenyl)-2-(4-piperidinyl)-5-thiazolyl]-2-pyrimidinaminedihydrochloride
• Formula: C21H22FN5S.2HCl
• Molecular Weight: 468.42
• Purity: >98 %
• Description: p38 MAPK inhibitor. Supresses p38 phosphorylation and LPS-induced TNF- α production in macrophages and in vivo . Attenuates zymosan-induced inflammation and adjuvant-induced arthritis in murine models. Orally active.