7,8-Dihydroxyflavone

• Supplier: Tocris Bioscience
• Catalog: 6277
• Function Type: Agonist
• Cas Number: 38183-03-8
• Chemical Name: 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one
• Formula: C15H10O4
• Molecular Weight: 254.24
• Purity: >98 %
• Description: Tyrosine kinase receptor B (TrkB) agonist that binds to the extracellular domain of the receptor (K d = 320 nM). Inhibits glutamate-triggered apoptosis in hippocampal neurons in vitro and in vivo . Exhibits neuroprotective effects in an HD mouse model.