Elacridar hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 6294
• Function Type: Inhibitor
• Cas Number: 143851-98-3
• Chemical Name: N-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamidehydrochloride
• Formula: C34H33N3O5.HCl
• Molecular Weight: 600.1
• Purity: >98 %
• Description: P-glycoprotein (P-gp/ABCG1) inhibitor. Blocks P-gp-mediated multidrug resistance (MDR) of the cytotoxic drugs doxorubicin (Cat. No. 2252) and vincristine (Cat. No. 1257) in CHRC5 cells. Also inhibits breast cancer resistance protein (BCRP/ABCG2). Orally active.