Name | ER 27319 maleate |
---|---|
Supplier | Tocris Bioscience |
Catalog | 6158 |
Function Type | Inhibitor |
Cas Number | 1204480-26-1 |
Chemical Name | 10-(3-Aminopropyl)-3,4-dimethyl-9(10H)-acridinonemaleate |
Formula | C18H20N2O.C4H4O4 |
Molecular Weight | 396.17 |
Purity | >99 % |
Description | Selective inhibitor of Syk kinase. Inhibits tyrosine phosphorylation of Syk initiated by the engagement of Fc ε RI in rat and human mast cells. Results in the abrogation of degranulation, TNF- α production (IC 50 = 10 μ M) and other related signaling events. |
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