ER 27319 maleate

Name ER 27319 maleate
Supplier Tocris Bioscience
Catalog 6158
Function Type Inhibitor
Cas Number 1204480-26-1
Chemical Name 10-(3-Aminopropyl)-3,4-dimethyl-9(10H)-acridinonemaleate
Formula C18H20N2O.C4H4O4
Molecular Weight 396.17
Purity >99 %
Description Selective inhibitor of Syk kinase. Inhibits tyrosine phosphorylation of Syk initiated by the engagement of Fc ε RI in rat and human mast cells. Results in the abrogation of degranulation, TNF- α production (IC 50 = 10 μ M) and other related signaling events.
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