Fasudil hydrochloride

Name Fasudil hydrochloride
Supplier Tocris Bioscience
Catalog 6100
Function Type Inhibitor
Cas Number 105628-07-7
Formula C14H17N3O2S.HCl
Molecular Weight 327.83
Purity >98 %
Description Cyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor (IC 50 = 10.7 μ M). Suppress MMP-2 expression and induce apoptosis in glioblastoma cells in vivo . Ca 2+ antagonist and vasodilator. Also inhibits proliferation of vascular smooth muscle cells.
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