27-Hydroxycholesterol

Name 27-Hydroxycholesterol
Supplier Tocris Bioscience
Catalog 5741
Function Type Agonist
Cas Number 20380-11-4
Chemical Name (3β,25R)-Cholest-5-ene-3,26-diol
Formula C27H46O2
Molecular Weight 402.65
Purity >98 %
Description Liver X receptor (LXR) agonist. Also estrogen receptor partial agonist. Suppresses β -estradiol -mediated breast cancer cell proliferation in vitro . Also increases α -synuclein levels and induces apoptosis in human neuroblastoma cells in vitro . Endogenous cholesterol metabolite.
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