JHW 007 hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 4322
• Function Type: Inhibitor
• Cas Number: 202645-74-7
• Chemical Name: (3-endo)-3-[Bis(4-fluorophenyl)methoxy]-8-butyl-8-azabicyclo[3.2.1]octanehydrochloride
• Formula: C24H29F2NO.HCl
• Molecular Weight: 421.95
• Purity: >99 %
• Description: Dopamine uptake inhibitor; displays high affinity for the dopamine transporter (DAT) (K i = 25 nM compared to 1330 and 1730 for NET and SERT respectively). Suppresses the effects of cocaine administration in a dose-dependent manner and decreases cocaine and methamphetamine self-administration in rats.