Napabucasin

• Supplier: Tocris Bioscience
• Catalog: 6183
• Function Type: Inhibitor
• Cas Number: 83280-65-3
• Chemical Name: 2-Acetylnaphtho[2,3-b]furan-4,9-dione
• Formula: C14H8O4
• Molecular Weight: 240.21
• Purity: >98 %
• Description: STAT3 inhibitor. Blocks spherogenesis of cancer stem cells (CSC), but not hematopoietic stem cells. Inhibits PaCa-2 xenograft tumor growth in mice, even after cessation of treatment, and decreases population of CSCs in PaCa-2 tumors from treated mice. Also blocks spleen and liver metastases of colon cancer cells in a mouse model.