NBD 556

Name NBD 556
Supplier Tocris Bioscience
Catalog 6121
Cas Number 333353-44-9
Chemical Name N1-(4-Chlorophenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)ethanediamide
Formula C17H24ClN3O2
Molecular Weight 337.84
Purity >98 %
Description CD4 mimetic (IC 50 values are in low micromolar range, dependent on cell type and HIV strain). Recognizes and induces structural changes in HIV-1 envelope protein gp120, analogous to CD4 binding. Inhibits HIV-1 cell entry in CXCR4 and CCR5 expressing cell lines, by blocking virus-cell and cell-cell fusion.
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