Nefazodone hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 5976
• Function Type: Antagonist
• Cas Number: 82752-99-6
• Chemical Name: 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-onehydrochloride
• Formula: C25H32ClN5O2.HCl
• Molecular Weight: 506.47
• Purity: >99 %
• Description: Serotonin 5-HT 2A receptor antagonist (K i = 5.8 nM) and inhibitor of serotonin and noradrenalin uptake (IC 50 values are 290 and 300 nM respectively). Displays no activity at 5-HT 1B and 5-HT 1D receptors. Active in models predictive of antidepressant potential.