17-PA

• Supplier: Tocris Bioscience
• Catalog: 6150
• Function Type: Antagonist
• Cas Number: 694438-95-4
• Chemical Name: 17-Phenyl-(3α,5α)-androst-16-en-3-ol
• Formula: C25H34O
• Molecular Weight: 350.54
• Purity: >99 %
• Description: Selective antagonist of neurosteroid potentiation and direct gating of GABA A receptors. Selectively reduces the effects of 5 α -reduced steroids compared to 5 β -reduced steroids and displays no effect on potentiation evoked by barbiturates and benzodiazepines. Attenuates 3 α ,5 α -THP-induced loss of righting reflex and total sleep time following i.c.v administration in rats.