STO-609 acetate

Name STO-609 acetate
Supplier Tocris Bioscience
Catalog 6036
Function Type Inhibitor
Cas Number 1173022-21-3
Chemical Name 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylicacidacetate
Formula C19H10N2O3.C2H4O2
Molecular Weight 374.35
Purity >98 %
Description Selective, cell-permeable inhibitor of Ca 2+ -calmodulin-dependent protein kinase kinase (K i values are 80 and 15 ng/ml for inhibition of CaM-KK α and CaM-KK β respectively); competes for the ATP-binding site. Displays > 80-fold selectivity over CaMK1, CaMK2, CaMK4, MLCK, PKC, PKA and p42 MAPK.
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