TPPU

• Supplier: Tocris Bioscience
• Catalog: 5343
• Function Type: Inhibitor
• Cas Number: 1222780-33-7
• Chemical Name: N-[1-(1-Oxopropyl)-4-piperidinyl]-N'-[4-(trifluoromethoxy)phenyl]urea
• Formula: C16H20F3N3O3
• Molecular Weight: 359.34
• Purity: >98 %
• Description: Potent soluble epoxide hydrolase (sEH) inhibitor (IC 50 values are 1.1 and 2.1 nM for murine and human receptor, respectively). Inhibits MAPK and NF- κ B signaling, as well as reducing ER stress and cell death in models of pancreatitis. Exhibits antidepressant effects in a social defeat stress model. Orally bioavailable and brain penetrant.