Vialinin A

• Supplier: Tocris Bioscience
• Catalog: 6156
• Function Type: Inhibitor
• Cas Number: 858134-23-3
• Chemical Name: 1,1'-(4,4'',5',6'-Tetrahydroxy[1,1':4',1''-terphenyl]-2',3'-diyl)benzeneaceticacidester
• Formula: C34H26O8
• Molecular Weight: 562.57
• Purity: >98 %
• Description: Inhibitor of ubiquitin-specific peptidase 4 (USP4), USP5/isopeptidase T (IsoT) and UCH-L1 deubiquitinating enzyme (DUB) activity (IC 50 values are 1.5, 5.9 and 22.3 μ M, respectively). Shows no significant inhibition of UCH-L3, USP2, and USP8 activities. Decreases release of TNF- α (IC 50 = 0.09 nM) from RBL-2H3 mast cells. Displays anti-cancer activity decreasing viability in human colonic carcinoma cells.