Name | FATP2 Inhibitor, CB-2 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 500670 |
Formula | C₁₇H₁₁BrClNO₃S₂ |
Purity | ≥99% by HPLC |
Description | A cell permeable thioxothiazolindine compound that reversibly inhibits FATP2- (fatty acid transport protein 2) mediated long chain fatty acid uptake in Caco-2 and HepG2, but not non-FATP2-expressing 3T3-L1 adipocytes, cultures (IC 50 against C 1 -BODIPY-C 12 = 3.99, 7.55, and 231.1 µM, respectively), exhibiting much reduced potency toward cellular Acsl (acyl-CoA synthetase) activity (IC 50 = 50 µM using lysates from 1h inhibitor-treated Caco-2 cells) |
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