H 89 dihydrochloride

Name H 89 dihydrochloride
Supplier BioGems
Catalog 1303954
Prices $85.00, $325.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 130964-39-5
Chemical Name N-[2-[[(E)-3-(4-bromophenyl)prop-2-enyl]amino]ethyl]isoquinoline-5-sulfonamide;hydrate;dihydrochloride
Formula C20H20BrN3O2S2HCl
Molecular Weight 519.3
Purity ≥98%
Description H 89 is a potent PKA inhibitor and an inhibitor for other protein kinases including S6K1, MSK1, ROCKII, PCKalpha, and MAPKAP-K1b. It has been shown to decrease morphine withdrawal symptoms in mice and to inhibit the forsolin-induced neurite outgrowth of PC12D pheochromocytoma cells.
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