Wnt-C59

Name Wnt-C59
Supplier BioGems
Catalog 1248913
Prices $155.00, $655.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 1243243-89-1
Chemical Name 2-[4-(2-methylpyridin-4-yl)phenyl]-N-(4-pyridin-3-ylphenyl)acetamide
Formula C25H21N3O
Molecular Weight 379.5
Purity ≥98%
Description Wnt-C59 is a highly potent Porcupine (PORCN) inhibitor that prevents Wnt-3a palmitoylation, secretion and activation (IC50=74pM). It is reported to inhibit cancer cell proliferation in cancer cell lines depended on Wnt activity. Together with CHIR 99021, Wnt-C59 can be used to induce cardiomyocyte differentiation from human induced pluripotent stem cells (iPSCs).
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