DNQX disodium salt

• Supplier: Abcam
• Catalog: ab120169
• Pubchem: 45073428
• Chemical Name: 6,7-Dinitroquinoxaline-2,3-dione disodium salt
• Formula: C8H2N4Na2O6
• Molecular Weight: 296.11
• Purity: > 99%
• Description: AMPA / kainate antagonist; water soluble

Product images

ab96379 staining MEK1 (phospho S298) in SK-N-SH cells treated with DNQX disodium salt (ab120169), by ICC/IF. Decrease in MEK1 (phospho S298) expression correlates with increased concentration of DNQX disodium salt, as described in literature.The cells were incubated at 37°C for 3h in media containing different concentrations of ab120169 (DNQX disodium salt) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab96379 (1/100 dilution) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody.

Product References

Modulation of short-term plasticity in the corticothalamic circuit by group III - Modulation of short-term plasticity in the corticothalamic circuit by group III

Kyuyoung CL, Huguenard JR. J Neurosci. 2014 Jan 8;34(2):675-87.

Modulation of short-term plasticity in the corticothalamic circuit by group III - Modulation of short-term plasticity in the corticothalamic circuit by group III

Kyuyoung CL, Huguenard JR. J Neurosci. 2014 Jan 8;34(2):675-87.

Transition to addiction is associated with a persistent impairment in synaptic - Transition to addiction is associated with a persistent impairment in synaptic

Kasanetz F, Deroche-Gamonet V, Berson N, Balado E, Lafourcade M, Manzoni O, Piazza PV. Science. 2010 Jun 25;328(5986):1709-12.