Dynasore

• Supplier: Abcam
• Catalog: ab120192
• Cas Number: 304448-55-3
• Chemical Name: 3-Hydroxynaphthalene-2-carboxylic acid (3,4-dihydroxybenzylidene)hydrazide
• Formula: C18H14N2O4
• Molecular Weight: 322.31
• Purity: > 99%
• Description: Cell-permeable dynamin inhibitor

Product images

ab66705 staining PAI1 in HeLa cells treated with dynasore (ab120192), by ICC/IF. Increase in PAI1 expression correlates with increased concentration of dynasore, as described in literature.The cells were incubated at 37°C for 6h in media containing different concentrations of ab120689 (dynasore) in DMSO, fixed with 100% methanol for 5 minutes at -20°C and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab66705 (5 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.

Product References

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Impact of dynasore an inhibitor of dynamin II on Shigella flexneri infection. - Impact of dynasore an inhibitor of dynamin II on Shigella flexneri infection.

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Building a better dynasore: the dyngo compounds potently inhibit dynamin and - Building a better dynasore: the dyngo compounds potently inhibit dynamin and

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