GF 109203X (Bisindolylmaleimide i)
| Name | GF 109203X (Bisindolylmaleimide i) |
|---|---|
| Supplier | Abcam |
| Catalog | ab144264 |
| Cas Number | 133052-90-1 |
| Pubchem | 2396 |
| Chemical Name | 3-[1-[3-(Dimethylamino)propyl]indol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione |
| Formula | C25H24N4O2 |
| Molecular Weight | 412.48 |
| Purity | > 98% |
| Description | Potent, selective PKC inhibitor. Potent GSK-3 inhibitor. Potent 5-HT3 antagonist. |
| Supplier Page | Shop |
Product images
1.5 x 10e7 THP-1 cells were incubated with 100 nM GF 109203X (ab144264) or Ro 31-8220 mesylate (ab120374) for 30 minutes prior to activation with 10 µg x mL-1 PMA (Sigma) for 4 hours. Control cells were left without inhibitors or PMA. Cells were lysed in 1 mL of lysis buffer, and 30 µL were tested for PKC activity (duplicates; +/- SD).