Ifenprodil

Name Ifenprodil
Supplier Abcam
Catalog ab120111
Cas Number 23210-58-4
Chemical Name erythro-4-(2-(4-Benzylpiperidin-1-yl)-1-hydroxypropyl)phenol hemitartrate
Formula C21H27NO2.0.5C4H6O6
Molecular Weight 400.49
Purity > 99%
Description GluN2B (formerly NR2B)-preferring NMDA antagonist
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Product References

Triheteromeric NMDA receptors at hippocampal synapses. - Triheteromeric NMDA receptors at hippocampal synapses.

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Reinstatement of nicotine seeking is mediated by glutamatergic plasticity. - Reinstatement of nicotine seeking is mediated by glutamatergic plasticity.

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Double dissociation of the requirement for GluN2B- and GluN2A-containing NMDA - Double dissociation of the requirement for GluN2B- and GluN2A-containing NMDA

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Amino-terminal ligands prolong NMDA Receptor-mediated EPSCs. - Amino-terminal ligands prolong NMDA Receptor-mediated EPSCs.

Tovar KR, Westbrook GL. J Neurosci. 2012 Jun 6;32(23):8065-73.

Chronic zinc exposure decreases the surface expression of NR2A-containing NMDA - Chronic zinc exposure decreases the surface expression of NR2A-containing NMDA

Zhu J, Shao CY, Yang W, Zhang XM, Wu ZY, Zhou L, Wang XX, Li YH, Xia J, Luo JH, Shen Y. PLoS One. 2012;7(9):e46012.

Functional refinement in the projection from ventral cochlear nucleus to lateral - Functional refinement in the projection from ventral cochlear nucleus to lateral

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Heroin relapse requires long-term potentiation-like plasticity mediated by - Heroin relapse requires long-term potentiation-like plasticity mediated by

Shen H, Moussawi K, Zhou W, Toda S, Kalivas PW. Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19407-12. doi: