Ionomycin (free acid)
| Name | Ionomycin (free acid) |
|---|---|
| Supplier | Abcam |
| Catalog | ab120370 |
| Cas Number | 56092-81-0 |
| Pubchem | 6912226 |
| Chemical Name | (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid |
| Formula | C41H72O9 |
| Molecular Weight | 709.01 |
| Purity | > 99% |
| Description | Ca2+ ionophore |
| Supplier Page | Shop |
Product images
ab58668 staining ATF3 in A549 cells treated with ionomycin (free acid) (ab120370), by ICC/IF. Increase in ATF3 expression correlates with increased concentration of ionomycin (free acid), as described in literature.The cells were incubated at 37°C for 2h in media containing different concentrations of ab120370 (Ionomycin (free acid)) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab58668 (10 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-mouse polyclonal antibody (ab96879) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.
Product References
Activity-dependent cleavage of the K-Cl cotransporter KCC2 mediated by - Activity-dependent cleavage of the K-Cl cotransporter KCC2 mediated by
Puskarjov M, Ahmad F, Kaila K, Blaesse P. J Neurosci. 2012 Aug 15;32(33):11356-64.
Ca2+-activated transbilayer movement of plasma membrane phospholipids in - Ca2+-activated transbilayer movement of plasma membrane phospholipids in
Weingartner A, dos Santos MG, Drobot B, Pomorski TG. Mol Biochem Parasitol. 2011 Oct;179(2):59-68. doi: