Ivermectin
| Name | Ivermectin |
|---|---|
| Supplier | Abcam |
| Catalog | ab141813 |
| Cas Number | 70288-86-7 |
| Pubchem | 6440492 |
| Chemical Name | 22,23-Dihydroavermectin B1a |
| Formula | C48H74O14 |
| Molecular Weight | 875.09 |
| Purity | > 96% |
| Description | Positive allosteric modulator of α7 nicotinic acetylcholine receptors |
| Supplier Page | Shop |
Product images
Ivermectin activates a7 nicotinic AChR heterologously expressed in Xenopus oocytes. Current traces of a7 nicotinic AChR at -80mV holding potential. Currents were elicited by applications 10 µM acetylcholine every 50 seconds. Increases of these induced currents were achieved upon perfusion of 10 µM Ivermectin (ab141813), as indicated by the horizontal bar.