(+)-MK 801 maleate (Dizocilpine)

• Supplier: Abcam
• Catalog: ab120027
• Cas Number: 77086-22-7
• Pubchem: 6420042
• Chemical Name: (5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate
• Formula: C16H15N.C4H4O4
• Molecular Weight: 337.37
• Purity: > 99%
• Description: Non-competitive NMDA antagonist

Product images

CDPPB does not influence spontaneous locomotor activity but attenuates MK-801-induced hyperlocomotion. Animals were injected (s.c./i.p.) with PBS/Vehicle (0/0), 0.2 mg/kg MK-801/Vehicle (0.2/0), 0.2 mg/kg MK-801/3 mg/kg CDPPB (0.2/3) or 0.2 mg/kg MK-801/10 mg/kg CDPPB (0.2/10) 20 minutes before being placed in the activity chamber. Activity was recorded for 30 minutes. Data are expressed as mean ± SEM of distance traveled (n=6-7). **p<0.01 vs. 0.2 mg/kg MK-801/Vehicle group (One-way ANOVA, Bonferroni’s posttest).

Product References

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