Mevastatin sodium salt
| Name | Mevastatin sodium salt |
|---|---|
| Supplier | Abcam |
| Catalog | ab120854 |
| Chemical Name | (βR,δR,1S,2S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid monosodium salt |
| Formula | C23H35NaO6 |
| Molecular Weight | 430.52 |
| Purity | > 98% |
| Description | HMG-CoA reductase inhibitor |
| Supplier Page | Shop |
Product images
ab90529 staining cytochrome C in HepG2 cells treated with mevastatin sodium salt (ab120854), by ICC/IF. Increase of cytochrome C expression correlates with increased concentration of mevastatin sodium salt, as described in literature.The cells were incubated at 37°C for 4 hours in media containing different concentrations of ab120854 (mevastatin sodium salt) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab90529 (1 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.