MiTMAB™
| Name | MiTMAB™ |
|---|---|
| Supplier | Abcam |
| Catalog | ab120466 |
| Cas Number | 1119-97-7 |
| Pubchem | 14250 |
| Chemical Name | Tetradecyltrimethylammonium bromide |
| Formula | C17H38BrN |
| Molecular Weight | 336.40 |
| Description | Cell-permeable dynamin I and dynamin II inhibitor |
| Supplier Page | Shop |
Product images
ab66705 staining PAI1 in HeLa cells treated with MiTMAB™ (ab120466), by ICC/IF. Increase in PAI1 expression correlates with increased concentration of MiTMAB™, as described in literature.The cells were incubated at 37°C for 24h in media containing different concentrations of ab120466 (MiTMAB™) in DMSO, fixed with 100% methanol for 5 minutes at -20°C and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab66705 (5 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.
Product References
Dynamic catch of a Thy-1-alpha5beta1+syndecan-4 trimolecular complex. - Dynamic catch of a Thy-1-alpha5beta1+syndecan-4 trimolecular complex.
Fiore VF, Ju L, Chen Y, Zhu C, Barker TH. Nat Commun. 2014 Sep 12;5:4886.
Reversal of dopamine D2 agonist-induced inhibition of ventral tegmental area - Reversal of dopamine D2 agonist-induced inhibition of ventral tegmental area
Nimitvilai S, McElvain MA, Brodie MS. J Pharmacol Exp Ther. 2013 Jan;344(1):253-63.