PD 153035
| Name | PD 153035 |
|---|---|
| Supplier | Abcam |
| Catalog | ab141839 |
| Cas Number | 153436-54-5 |
| Pubchem | 4705 |
| Chemical Name | N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-amine |
| Formula | C16H14BrN3O2 |
| Molecular Weight | 360.21 |
| Purity | > 99% |
| Description | Highly potent and selective EGFR inhibitor |
| Supplier Page | Shop |
Product images
PD 153035 inhibits EGF receptor activation in 3T3-L1 cells. Cells were serum starved for 3 h and preincubated with different concentrations of PD 153035 (ab141839) for 2 h. The cells were then stimulated with 200 ng/ml EGF for 10 minutes. Cell proteins were resolved by SDS-PAGE and probed with anti-phospho-EGFr (upper panel) and with anti-phospho ERK1/2 (lower panel).