Phrixotoxin-1
| Name | Phrixotoxin-1 |
|---|---|
| Supplier | Abcam |
| Catalog | ab141844 |
| Cas Number | 221872-97-5 |
| Chemical Name | YCQKWMWTCDSARKCCEGLVCRLWCKKII (Modifications: Ile-29= C-terminal amide; Disulfide bridges: 2-16, 9-21 and 15-25) |
| Formula | C156H240N44O37S7 |
| Molecular Weight | 3549.00 |
| Purity | > 98% |
| Description | Specific Kv4.3 and Kv4.2 channel blocker |
| Supplier Page | Shop |
Product images
Phrixotoxin-1 inhibits KV4.2 currents expressed in Xenopus oocytes. KV4.2 channel currents were recorded using two electrode voltage clamp, with ND 96 in the bath solution. From a holding potential of -100 mV to -10 mV, a 100 ms depolarization was applied every 10 sec in the before (black) or during (green) the application of 100 nM Phrixotoxin-1 (ab141844).