(R,S)-AMPA
| Name | (R,S)-AMPA |
|---|---|
| Supplier | Abcam |
| Catalog | ab120130 |
| Cas Number | 74341-63-2 |
| Pubchem | 1221 |
| Chemical Name | (RS)-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid |
| Formula | C7H10N2O4 |
| Molecular Weight | 186.17 |
| Purity | > 99% |
| Description | AMPA agonist |
| Supplier Page | Shop |
Product images
ab96379 staining MEK1 (phospho S298) in SK-N-SH cells treated with (R,S)-AMPA (ab120130), by ICC/IF. Increase in MEK1 (phospho S298) expression correlates with increased concentration of(R,S)-AMPA, as described in literature.The cells were incubated at 37°C for 24h in media containing different concentrations of ab120130 ((R,S)-AMPA) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab96379 (1/100 dilution) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody.
Product References
Switch to glutamate receptor 2-lacking AMPA receptors increases neuronal - Switch to glutamate receptor 2-lacking AMPA receptors increases neuronal
Li DP, Byan HS, Pan HL. J Neurosci. 2012 Jan 4;32(1):372-80.
Intracellular Ca2+ release through ryanodine receptors contributes to AMPA - Intracellular Ca2+ release through ryanodine receptors contributes to AMPA
Ruiz A, Matute C, Alberdi E. Cell Death Dis. 2010 Jul 15;1:e54.
Protein SUMOylation modulates calcium influx and glutamate release from - Protein SUMOylation modulates calcium influx and glutamate release from
Feligioni M, Nishimune A, Henley JM. Eur J Neurosci. 2009 Apr;29(7):1348-56.
Targeted disruption of cocaine-activated nucleus accumbens neurons prevents - Targeted disruption of cocaine-activated nucleus accumbens neurons prevents
Koya E, Golden SA, Harvey BK, Guez-Barber DH, Berkow A, Simmons DE, Bossert JM, Nair SG, Uejima JL, Marin MT, Mitchell TB, Farquhar D, Ghosh SC, Mattson BJ, Hope BT. Nat Neurosci. 2009 Aug;12(8):1069-73.