(R,S)-MCPG
| Name | (R,S)-MCPG |
|---|---|
| Supplier | Abcam |
| Catalog | ab120033 |
| Cas Number | 146669-29-6 |
| Pubchem | 1222 |
| Chemical Name | (R,S)-α-Methyl-4-carboxyphenylglycine |
| Formula | C10H11NO4 |
| Molecular Weight | 209.20 |
| Purity | > 99% |
| Description | Group I /II metabotropic glutamate antagonist |
| Supplier Page | Shop |
Product images
ab17722 staining FMRP in SK-N-SH cells treated with (R,S)-MCPG (ab120033), by ICC/IF. Decrease in FMRP expression correlates with increased concentration of (R,S)-MCPG, as described in literature.The cells were incubated at 37°C for 2h in media containing different concentrations of ab120033 ((R,S)-MCPG) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab17722 (5 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.
Product References
Late-onset bursts evoked by mossy fibre bundle stimulation in unipolar brush - Late-onset bursts evoked by mossy fibre bundle stimulation in unipolar brush
Locatelli F, Botta L, Prestori F, Masetto S, D'Angelo E. J Physiol. 2013 Feb 15;591(Pt 4):899-918.
A human mutation in Gabrg2 associated with generalized epilepsy alters the - A human mutation in Gabrg2 associated with generalized epilepsy alters the
Bouthour W, Leroy F, Emmanuelli C, Carnaud M, Dahan M, Poncer JC, Levi S. Cereb Cortex. 2012 Jul;22(7):1542-53.