Ro 31-8220 mesylate (Bisindolylmaleimide IX)
| Name | Ro 31-8220 mesylate (Bisindolylmaleimide IX) |
|---|---|
| Supplier | Abcam |
| Catalog | ab120374 |
| Cas Number | 125314-64-9 |
| Pubchem | 11628205 |
| Chemical Name | 3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione methanesulfonate |
| Formula | C25H23N5O2S.CH3SO3H |
| Molecular Weight | 553.65 |
| Purity | > 98% |
| Description | Protein kinase inhibitor |
| Supplier Page | Shop |
Product images
1.5 x 10e7 THP-1 cells were incubated with 100 nM GF 109203X (ab144264) or Ro 31-8220 mesylate (ab120374) for 30 minutes prior to activation with 10 µg x mL-1 PMA (Sigma) for 4 hours. Control cells were left without inhibitors or PMA. Cells were lysed in 1 mL of lysis buffer, and 30 µL were tested for PKC activity (duplicates; +/- SD).