| Gene Symbol |
IFT88
|
| Entrez Gene |
8100
|
| Alt Symbol |
D13S1056E, DAF19, TG737, TTC10, hTg737
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
intraflagellar transport 88
|
| Other Description |
TPR repeat protein 10|intraflagellar transport 88 homolog|intraflagellar transport protein 88 homolog|polaris homolog|probe hTg737 (polycystic kidney disease, autosomal recessive)|recessive polycystic kidney disease protein Tg737 homolog|tetratricopeptide repeat domain 10|tetratricopeptide repeat protein 10
|
| Swissprots |
A2A491 Q8N719 B4DUS2 Q5SZJ6 Q13099
|
| Accessions |
EAX08266 EAX08267 EAX08268 EAX08269 EAX08270 EAX08271 EAX08272 EAX08273 Q13099 AK058172 AK126668 BAG54354 AK300769 BAG62434 AK303853 BAG64794 AK308281 AK310223 BC030776 AAH30776 BC059357 BG182322 BX640833 CAE45907 DQ572744 EU176190 ABW03641 EU176494 ABW03295 U20362 AAA86720 XM_005266546 XP_005266603 XM_005266547 XP_005266604 XM_005266548 XP_005266605 XM_005266549 XP_005266606 XM_005266550 XP_005266607 XM_005266551 XP_005266608 XM_005266552 XP_005266609 XM_005266553 XP_005266610 XM_005266555 XP_005266612 XM_006719870 XP_006719933 XM_011535240 XP_011533542 XM_011535241 XP_011533543 XM_011535242 XP_011533544 XM_011535243 XP_011533545 XM_011535244 XP_011533546 XM_011535245 XP_011533547 XM_011535246 XP_011533548 XR_245399 XR_941663 NM_006531 NP_006522 NM_175605 NP_783195
|
| Function |
Involved in primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}.
|
| Tissue Specificity |
Expressed in the heart, brain, liver, lung, kidney, skeletal muscle and pancreas. {ECO:0000269|PubMed:7633404}.
|
![Western Blot: IFT88 Overexpression Lysate (Adult Normal) [NBL1-11863] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for IFT88.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/956_IFT88%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11863-img0002.jpg)
![Western Blot: IFT88 Overexpression Lysate (Adult Normal) [NBL1-11864] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for IFT88.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/7589_IFT88%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-11864-img0002.jpg)